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. 2012 Dec 12;2012(12):CD008650. doi: 10.1002/14651858.CD008650.pub2

Hursel 2009.

Methods The was a randomised, placebo‐controlled, double‐blind parallel trial with a treatment to control randomisation ratio of 1:1
Participants INCLUSION CRITERIA:
  • 18 to 60 years old

  • BMI: 25 to 35 kg/m2

  • in good health

  • non‐smoker

  • not using medication

  • ingesting ≤ 100 mg caffeine/day (from coffee, tea, chocolate, cola or energy drinks; main source of caffeine intake was coffee)

  • not drinking green tea habitually

  • moderate alcohol user at most


EXCLUSION CRITERIA: NR
DIAGNOSTIC CRITERIA:
  • weight (measured with a digital balance ‐ model 707; Seca, Hamburg, Germany; weighing accuracy of 0.1 kg ‐ participants in underwear, in a fasted state, after emptying their bladder)

  • height (measured with a wall‐mounted stadiometer‐ model 220; Seca)

  • BMI (calculated from previous 2 measurements)

  • distribution of fat (measured using waist circumference at site of the smallest circumference between rib cage and ileac crest in standing position)

Interventions NUMBER OF STUDY CENTRES: NR
COUNTRY/ LOCATION: the Netherlands
SETTING: NR
TREATMENT BEFORE STUDY:
participants were required to enter 4 weeks of weight loss before study for weight maintenance began
Outcomes OUTCOME(S) (as stated in the protocol/registered trial documents):
PRIMARY OUTCOME(S): unknown
SECONDARY OUTCOME(S): unknown
OTHER OUTCOME(S): unknown
Study details STUDY TERMINATED BEFORE REGULAR END: no
Publication details This study was published in English in The American Journal of Clinical Nutrition, a peer‐reviewed journal, and was supported by NUTRIM, Maastricht University, Maastricht, Netherlands.
Stated aim of study Quote from study: "the following study addresses this research question, with the aim to investigate whether a green tea–caffeine mixture added to an HP [high protein] diet may improve weight maintenance by preventing or limiting weight regain after weight loss of 5–10% in moderately obese subjects with a low habitual caffeine intake"
Notes BMI: body mass index; NR: not reported
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote from study: "subjects were randomly assigned to 4 groups"
Comment: method of randomisation not reported
Allocation concealment (selection bias) Unclear risk Comment: not reported
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Quote from study: "a randomised, placebo‐controlled, double‐blind parallel trial was conducted"
"A double‐blind administration of the supplementation (green tea‐caffeine mixture or placebo) was performed"
Comment: no description of capsule product compared to placebo found. No mention of effectiveness of blinding efforts
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Comment: all outcomes on which the study reported were objective and measured by assessors. Therefore, whether or not assessors were blinded, risk of detection bias was assessed as low
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Comment: authors adequately accounted for attrition
Selective reporting (reporting bias) Low risk Comment: all outcome measurements stated in methods section were reported in the results
Other bias Low risk Comment: appears to be free of other bias