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. 2012 Dec 12;2012(12):CD008650. doi: 10.1002/14651858.CD008650.pub2

Wang 2010.

Methods This study was a randomised, double‐blind placebo‐controlled trial using a between‐subject design with a randomisation ratio of 1:1.04:0.91:0.91
Participants INCLUSION CRITERIA:
  • 18 to 55 years old

  • BMI 24 to 35 kg/m2

  • body fat > 25% for males and > 30% for females

  • waist circumference > 85 cm for males and > 80 cm for females

  • normal liver function (assessed by plasma enzyme profile and total bilirubin levels)

  • low caffeine consumption (< 200 mg/day)

  • low tea consumption (< 2 tea bags/day or < 4 g loose tea/day)

  • non‐smoking

  • zero or moderate (< 14/week for women and < 21/week for men) alcohol consumption


EXCLUSION CRITERIA:
  • use of any medication, except over‐the‐counter and oral contraceptives

  • suffering from any medical or psychiatric condition

  • actively following a weight loss regimen or a medically prescribed dietary regimen

  • change in body weight  > 2 kg in 3 months before start of trial


DIAGNOSTIC CRITERIA:
  • body fat % (measured with a QDR4500W Dexa (fan beam) (Hologic, Waltham, MA))

  • body weight

  • waist circumference

  • hip circumference

Interventions NUMBER OF STUDY CENTRES: 1
COUNTRY/ LOCATION: China/Shanghai
SETTING: study centre
TREATMENT BEFORE STUDY:
note: run‐in period of 2 weeks where participants drank 1 serving of control tea at study site to test adherence and protocol compliance
Outcomes OUTCOME(S) (as stated in the protocol/registered trial documents):
PRIMARY OUTCOME(S): unknown
SECONDARY OUTCOME(S): unknown
OTHER OUTCOME(S): unknown
Study details STUDY TERMINATED BEFORE REGULAR END: no
Publication details This study was published in English in Obesity, a peer‐reviewed journal, and was supported by the Lipton Institute of Tea; all authors but 1 were employees of Unilever
Stated aim of study Quote from study: "in this large, double‐blind placebo‐controlled trial we investigated the effects of consuming GT [green tea] with different amounts of catechins on measures of body weight, total body fat mass and the distribution of fat between abdominal and other depots"
Notes BMI: body mass index
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote from study: "subjects were randomly allocated to one of four groups. Randomization of subjects into experimental groups was based on stratification by BMI, waist circumference/height, and gender"
Comment: Method of randomisation not reported.
Allocation concealment (selection bias) Unclear risk Comment: not reported
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Quote from study: "to ensure that subjects would not know they were consuming a control treatment, a small amount of unextracted green leaf (0.5 g) and tea power perfume were added"
Comment: No mention of whether investigators were blinded as well. No mention of effectiveness of blinding efforts
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Comment: all outcomes on which the study reported were objective and measured by assessors. Therefore, whether or not assessors were blinded, risk of detection bias was assessed as low
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Comment: authors adequately accounted for attrition
Selective reporting (reporting bias) Low risk Comment: outcomes specified at the beginning were adequately investigated and reported
Other bias Unclear risk Comment: authors are employees of Unilever or Lipton; nature of corporate support for study is unclear