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. 2021 Mar 18;2021(3):CD013881. doi: 10.1002/14651858.CD013881

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Flowchart of included RCTs of interleukin 6 (IL‐6) blocking agents (last search date 11 February 2021).

COVID‐NMA is a living systematic review of all trials assessing treatment and preventive interventions for COVID‐19 (Boutron 2020b). This review is a sub‐review of COVID‐NMA.

*two multiple‐arm RCTs evaluated both tocilizumab and sarilumab, one three‐arm RCT evaluated tocilizumab and siltuximab and consequently they appear twice. §one multi‐arm RCT evaluated both tocilizumab and sarilumab