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| Methods | Randomized parallel group, 24 weeks. | |
| Participants | 15 treatment, 15 control patients; comparable at baseline. | |
| Interventions | Epalrestat 150 mg vs "usual care". | |
| Outcomes | Electrophysiology. | |
| Notes | Also used pupillary and cardiovascular reflex outcomes. | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment? | Unclear risk | B ‐ Unclear |
