Table 2.
Association of AA exposure with the risk of NAFLD in whole group (n = 3234)
| HbAA | HbGA | HbGA/HbAA | ||||
|---|---|---|---|---|---|---|
| OR (95%CI) | Ptrend | OR (95%CI) | Ptrend | OR (95%CI) | Ptrend | |
| Model 1 | 0.001 | 0.145 | < 0.001 | |||
| Q1 (reference) | ||||||
| Q2 | 0.96 (0.73–1.25) | 1.24 (0.88–1.74) | 1.69 (1.34–2.13) | |||
| Q3 | 0.66 (0.52–0.85) | 1.27 (0.95–1.70) | 2.47 (2.02–3.02) | |||
| Q4 | 0.69 (0.52–0.91) | 1.28 (0.98–1.67) | 2.77 (2.15–3.57) | |||
| Model 2 | < 0.001 | 0.262 | < 0.001 | |||
| Q1 (reference) | ||||||
| Q2 | 0.92 (0.70–1.21) | 1.25 (0.89–1.76) | 1.60 (1.25–2.04) | |||
| Q3 | 0.65 (0.50–0.85) | 1.22 (0.88–1.70) | 2.24 (1.84–2.73) | |||
| Q4 | 0.64 (0.48–0.84) | 1.24 (0.93–1.64) | 2.72 (2.09–3.53) | |||
| Model 3 | < 0.001 | 0.998 | < 0.001 | |||
| Q1 (reference) | ||||||
| Q2 | 0.90 (0.68–1.19) | 1.07 (0.76–1.49) | 1.68 (1.34–2.11) | |||
| Q3 | 0.65 (0.49–0.85) | 1.10 (0.79–1.53) | 2.33 (1.85–2.94) | |||
| Q4 | 0.61 (0.46–0.81) | 1.15 (0.85–1.55) | 2.72 (2.06–3.58) | |||
Quartiles of HbAA: Q1, HbAA ≤ 36.10 pmol/g Hb; Q2, 36.10 < HbAA ≤ 47.60 pmol/g Hb; Q3, 47.60 < HbAA ≤ 66.50 pmol/g Hb; and Q4, HbAA > 66.50 pmol/g Hb
Quartiles of HbGA: Q1, HbGA ≤ 32.30 pmol/g Hb; Q2, 32.30 < HbGA ≤ 44.90 pmol/g Hb; Q3, 44.90 < HbGA ≤ 65.00 pmol/g Hb; and Q4, HbGA > 65.00 pmol/g Hb
Quartiles of HbGA/HbAA: Q1, ≤ 0.732; Q2, 0.732 < HbGA/HbAA ≤ 0.895; Q3, 0.895 < HbGA/HbAA ≤ 1.091; and Q4, HbGA/HbAA > 1.091
Model 1 was adjusted for demographic factors (age, gender, race/ethnicity, education levels, family PIR, marital status, and serum cotinine level)
Model 2 was adjusted for model 1 plus total fat intake and total energy intake
Model 3 was further adjusted for model 2 plus biochemistry factors (serum albumin, LDL-cholesterol, total cholesterol and blood platelet count)