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. 2021 Aug 30;20:98. doi: 10.1186/s12940-021-00783-2

Table 4.

Odds ratios for associations between HbAA and NAFLD in subgroups

Subgroups HbAA quartile (pmol/g Hb)a Ptrend Pinteraction
Q2 (36.10 < HbAA ≤ 47.60) Q3 (47.60 < HbAA ≤ 66.50) Q4 (HbAA > 66.50)
Age 0.130
  ≤ 50 years 0.93 (0.56–1.55) 0.80 (0.51–1.26) 0.66 (0.41–1.06) 0.032
  > 50 years 0.87 (0.66–1.13) 0.51 (0.37–0.70) 0.51 (0.34–0.78) 0.001
Gender 0.717
Male 0.95 (0.68–1.31) 0.75 (0.48–1.16) 0.64 (0.36–1.11) 0.102
Female 0.86 (0.60–1.23) 0.55 (0.39–0.75) 0.60 (0.36–1.01) 0.003
Race 0.006
Non-Hispanic white 0.82 (0.56–1.19) 0.56 (0.41–0.78) 0.51 (0.37–0.72)  < 0.001
Non-Hispanic black 1.03 (0.40–2.65) 1.06 (0.46–2.41) 0.58 (0.28–1.18) 0.228
Mexican American 0.77 (0.40–1.51) 0.46 (0.26–0.83) 0.69 (0.31–1.56) 0.115
Education levels 0.895
Under high school 1.57 (0.76–3.24) 0.63 (0.34–1.16) 0.80 (0.52–1.21) 0.017
High school 0.95 (0.55–1.62) 0.66 (0.39–1.11) 0.63 (0.30–1.34) 0.131
Above high school 0.76 (0.49–1.19) 0.64 (0.42–0.98) 0.53 (0.35–0.78) 0.005
Married 0.887
No 1.00 (0.67–1.47) 0.59 (0.36–0.98) 0.65 (0.45–0.92) 0.007
Yes 0.87 (0.63–1.22) 0.67 (0.49–0.90) 0.60 (0.42–0.88) 0.006
ALT  < 0.001
  ≤ 40 U/L 0.96 (0.69–1.34) 0.62 (0.45–0.86) 0.74 (0.54–1.01) 0.006
  > 40 U/L 0.45 (0.16–1.28) 0.36 (0.19–0.66) 0.32 (0.11–0.93) 0.014

aORs were compared to quartile1 (HbAA ≤ 36.10 pmol/g Hb), adjusted for full model