Study	Comparison	Time‐to‐complete wound healing	Proportion of wounds completely healed	Comments
Charles 1991	Group 1. Compression (short‐stretch bandage) Group 2. No compression	‐	Leg ulcers completely healed Group 1. 71% Group 2. 25%	Unit of analysis is probably ulcers. The authors concluded "the leg ulcers treated with the short‐stretch compression bandage had a statistically significant (chi‐square test) higher healing rate than those treated in the control group."
Daróczy 2006	Group 1. Compression (topical povidone‐iodine plus compression) Group 2. No compression (topical povidone‐iodine without compression)	‐	Group 1. 82% of 21 patients Group 2. 62% of 21 patients
Kikta 1988	Group 1. Compression (Unna’s boot) Group 2. No compression (hydroactive dressing)	Estimated results using Tierney 2007 methods: HR 2.38 95% CI 1.23 to 4.60 (lnHR 0.87 and selnHR 0.34)	Data included in Analysis 1.2 Group 1. 33/42 ulcers healed Group 2. 21/45 ulcers healed Data included in the associated sensitivity analysis of assuming missing data had unhealed leg ulcers Group 1. 21/42 ulcers healed Group 2. 15/45 ulcers healed.	Regarding the proportion of wounds completely healed, the difference in the data is due to the different assumptions applied for data analysis (see Sensitivity analysis).
Morrell 1998	Group 1. Compression (4‐layer bandaging) Group 2. No compression (usual care)	Group 1 compared with Group 2. Log rank test statistic 4.90 (df =1, P = 0.03); Univariate Cox analysis: HR 1.45 (95% CI 1.04 to 2.03); Multivariate Cox analysis: HR 1.65 (95% CI 1.15 to 2.35). Median healing time: Group 1. 20 weeks Group 2. 43 weeks Mean number of weeks the participants were free from ulcers: Group 1. 20.1 weeks Group 2. 14.2 (difference 5.9; 95% CI 1.2 to 10.5)	Number (%) patients with complete healing at 12 months Group 1. 78/120 (65%) Group 2. 62/113 (55%)
O'Brien 2003	Group 1. Compression (4‐layer bandage) Group 2. No compression	Group 1 compared with Group 2 HR 1.8 (95% CI 1.2 to 2.9)	Kaplan–Meier estimate of the proportion healed at 3 months Group 1. 54% Group 2. 34% (P < 0·001).
Rubin 1990	Group 1. Compression (Unna’s boot) Group 2. No compression (polyurethane foam dressing)	‐	ITT analysis: Group 1. 18/19 (94.7%) patients with ulcers healed Group 2. 7/17 (41.2%). Complete cases: Group 1. 18/19 (94.7%) Group 2. 7/8 (87.5%) (Chi‐squared = 8.2, P < 0.005).
Taradaj 2007	Group 1. Compression Group 2. No compression	‐	Narratives: No statistical difference in the pre‐ and post‐treatment changes of total surface area, volume, length, width, field, and granulation surface area among groups (P‐values of all between‐group comparisons > 0.05); the percentage of weekly wound surface change rates; and the percentage of weekly ulcer volume change rates.
Taylor 1998	Group 1. Compression Group 2.	Results calculated using the methods in Tierney 2007: HR 4.54 (95% CI 1.65 to 12.49); lnHR 1.51 and selnHR 0.52. Median healing time Group 1. 55 days Group 2. 84 days. (Lee‐Desu statistic 8.603, P = 0.0034).	Data used in Analysis 1.2 Group 1. 14/18 Group 2. 7/18 Data used in the associated sensitivity analysis of assuming missing data had unhealed leg ulcers Group 1. 12/18 Group 2. 3/18	Regarding the proportion of wounds completely healed, the difference in the data is due to the different assumptions applied for data analysis (see Sensitivity analysis).
Wong 2008a	Group 1. Compression (short‐stretch bandage, and 4‐layer bandage) Group 2. No compression	‐	Data used in Analysis 1.2 Group 1. 15/20 Group 2. 5/10 Data used in the associated sensitivity analysis of assuming missing data had unhealed leg ulcers Group 1. 13/20 Group 2. 3/10.	Regarding the proportion of wounds completely healed, the difference in the data is due to the different assumptions applied for data analysis (see Sensitivity analysis).
Wong 2008b	Group 1. Compression (short‐stretch bandage) Group 2. Compression (4‐layer bandage) Group 3. No compression	Cox regression adjusted for age, initial ulcer size, and ulcer duration (hazard ratios for healing for Group 1 and Group 2 relative to Group 3) HR 2.72 (95% CI= 1.53‐4.86); 3.14 (95% CI= 1.74‐5.67) Survival time Mean 7.831 weeks (SE 0.489) for SSB, 8.557 (0.430) for 4LB, 10.378 (0.383) for control.	Data analysed in Analysis 1.2: Group 1. 48/60 Group 2. 50/60 Group 3. 23/60. Data used in the associated sensitivity analysis of assuming missing data had unhealed leg ulcers Group 1. 38/60 Group 2. 36/60 Group 3. 17/60.	Regarding the proportion of wounds completely healed, the difference in the data is due to the different assumptions applied for data analysis (see Sensitivity analysis).
Wong 2012	Group 1. Compression (short‐stretch bandage) Group 2. Compression (4‐layer bandage) Group 3. No compression	Time‐to‐complete wound healing Group 1. mean 9.8 (SD 0.77) weeks Group 2. 10.4 (0.80) Group 3. 18.3 (0.86)	Week 12: Group 1. 66.4% (71 ⁄ 107) Group 2. 59.8% (64 ⁄ 107) Group 3. 28.0% (30 ⁄ 107). Week 24: Group 1. 72.0% (77 ⁄ 107) Group 2. 67.3% (72 ⁄ 107) Group 3. 29.0% (31 ⁄ 107)