| Methods |
Prospective study of sexually active HIV discordant heterosexual couples (incidence estimation and associated risk factors) |
| Participants |
‐ Italy, hospitals, IVDU outpatient clinics, HIV surveillance centers
‐ enrolled 2/87‐ 5/92
‐ M+F‐ couples (n=436)
‐ IC type: IVDU (predom.)
‐ partner exclusions: IVDU, prositutes, recipients of blood products |
| Interventions |
‐ counselling about HIV prevention, condom use, GYN exams
‐ @ 6mo sexual history, STD history, contraceptive history, HIV test |
| Outcomes |
Vaginal (and possibly anal) condom usage
‐ always (100%)
‐ not always/ never (0‐99%)
HIV serotesting by immunoenzymatic method, confirmed by Western blot |
| Notes |
‐ some ICs underwent zidovudine treatment (and had lower transmission)
‐ each time exposure considered independent (each person mihgt contribute to each category of condom use/ exposure time) |
