TABLE 5.
List of regulatory regions putatively involved in promoting competing abilities and capabilities of coinfecting nodulesa
| COG ID | COG class(es) | COG functional category | Prokka annotation/product | Biological process(es) |
|---|---|---|---|---|
| COG2132 | DMP | Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA) | Putative blue copper oxidase CueO | Detoxification of copper ion |
| COG2188 | K | DNA-binding transcriptional regulator, GntR family | Putative transcriptional repressor | DNA-binding transcriptional regulation |
| COG0559 | E | Branched-chain amino acid ABC-type transport system, permease component | High-affinity branched-chain amino acid transport system permease protein LivH | Branched-chain amino acid transport |
| COG1529 | C | CO or xanthine dehydrogenase, Mo-binding subunit | Putative caffeine dehydrogenase subunit alpha | Oxidation-reduction process |
| COG2124 | QV | Cytochrome P450 | Putative pentalenolactone synthase (cytochrome P450 CYP2 subfamily) | Pentalenolactone biosynthetic process |
a
COG description of supposed target orthologous genes of regulatory region hits identified by 14 top k-mers (P value 5.14 × 10−5) in the most competitive strains as single occupants and coinhabitants of mixed nodules (Sinorhizobium meliloti GR4, SM11, KH35c, KH46, AK58, and RU11/001).