TABLE 2.
Number of regulated transcripts and metabolite features shared by all members of a gyrase inhibitor class
| Class | No. genes upregulateda | No. genes downregulateda | No. features upregulateda | No. features downregulateda |
|---|---|---|---|---|
| Fluoroquinolones | 154 | 16 | 11 | 49 |
| Aminocoumarins | 206 | 297 | 33 | 142 |
| Cystobactamids | 83 | 8 | 37 | 8 |
Differentially expressed genes (fold change > 2, FDR < 0.05), differential abundance of metabolite features (fold change > 1.5, P < 0.05).