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Effect of PSO pretreatment on the level of pro-inflammatory cytokines in the serum. (A) IL-1β; (B) IL-6; (C) and TNF-α were determined by ELISA assay. Data are expressed as mean ± SEM, n = 3. **P < 0.01 and ***P < 0.001 indicate significant differences in comparison with DSS group. PSO, Perilla seed oil; DSS, dextran sulfate sodium; SSZ, sulfasalazine; IL, interleukin; TNF, tumor necrosis factor.
