Table 2.

The mean pathologic score of renal damage and glomerular histomorphometry were recorded in the kidneys of normal and treated groups. Data are presented as mean ± SEM, n = 10. Rats of the normal control group received intraperitoneal saline. Different lowercase letters are significantly different (P < 0.05).

Groups	Glomerular tuft area (μm2)	Mean pathologic score of renal damage
Normal control	4545.32c ± 285.37	0.1 ± 0.10
DXR-control (15 mg/kg, i.p)	10048.81a ± 1158.94	2.8a ± 0.13
DXR + SAX (10 mg/kg, p.o.)	7206.09b ± 555.98	0.9b ± 0.23
DXR + VIL (10 mg/kg, p.o.)	6095.86b,c ± 507.78	0.4b ± 0.16

DXR, Doxorubicin; SAX, saxagliptin; VIL, vildagliptin.