| Methods |
Allocation: "randomized", not further described.
Blinding: allocation stated to be concealed, otherwise no blinding described.
Study period: not stated. |
| Participants |
Inclusion criteria: women with PROM at 38‐41 weeks' gestation and no uterine contractions 3 hours after rupture.
Setting: University hospital Center, Dallas, Texas.
Number of participants: n = 100. |
| Interventions |
Oral PGE2 0.5 mg every 30‐60 minutes starting 3 hours after PROM for up to 6 hours (n = 50) vs no treatment until 12 hours after PROM (n = 50). For both groups IV oxytocin was begun at 12 hours after PROM if not in active labor. |
| Outcomes |
Time from PROM to delivery.
Fetal bradycardia.
Mode of delivery.
Gastrointestinal side‐effects. |
| Notes |
Subgroups were considered based on parity and Bishop score at 3 hours after PROM. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Low risk |
A ‐ Adequate |
