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. 2001 Apr 23;2001(2):CD003098. doi: 10.1002/14651858.CD003098

Lykkesfeldt 1981.

Methods Allocation: "randomized", not further described. 
 Blinding: none described. 
 Study period: not stated.
Participants Inclusion criteria: primiparous women with indication for induction of labor and Bishop score < 7. 
 Setting: University Hospital, Copenhagen, Denmark. 
 Number of participants: n = 132.
Interventions Oral PGE2 0.5 mg every 1/2 hour up to a dose of 5 mg in 24 hours vs demoxytocin 50 IU every 1/2 hour up to 500 IU in 24 hours vs demoxytocin in the 1st 24 hours and oral PGE2 the 2nd day.
Outcomes Successful induction within 48 hours. 
 Mode of delivery. 
 Gastrointestinal side‐effects. 
 Uterine hyperstimulation. 
 Apgar score < 7 at 1 minute.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear