Secher 1981.

Methods	Allocation: "random", not further described. Blinding: none described. Study period: not stated.
Participants	Inclusion criteria: women admitted for induction of labor with membranes intact, single live fetus in cephalic position. Setting: University hospital, Odense, Denmark. Number of participants: n = 471.
Interventions	Women with ripe cervix and head engaged (n = 227) underwent amniotomy and observation for 4 hours. 124 were in labor. The remainder (n = 103) received oral PGE2 0.5 mg increasing to 1.5 mg per hour if needed (n = 57) vs IV oxytocin to a maximum infusion rate of 45 miliunits per minute (n = 46). Those with unfavorable cervix: oral prostaglandin as above (n = 125) vs IV oxytocin as above (n = 119).
Outcomes	Length of labor. Treatment time. Apgar score. Mode of delivery. Gastrointestinal side‐effects.
Notes	IV oxytocin was given at a rapidly increasing rate, starting at 7.5 miliunits and increasing by 7.5 miliunits every 15 minutes.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Unclear risk	B ‐ Unclear