Westergaard 1983.
Methods | Allocation: sealed envelopes. Blinding: None described. Study period: 24 months, specific dates not stated. | |
Participants | Inclusion criteria: women admitted for induction of labor with single live fetus in cephalic position and membranes intact. Setting: University hospital, Odense, Denmark. | |
Interventions | Women with unfavorable cervix (n = 264): oral PGE2 0.5 mg increasing to 1.5 mg per hour if needed (n = 133) vs demoxytocin 50 IU every 1/2 hour (n = 131). Women with favorable cervix underwent amniotomy (n = 259 of which 136 progressed into labour within 4 hours without medication). The remaining 123 women received oral PGE2 as above (n = 48) vs demoxytocin as above (n = 75). |
|
Outcomes | Induction failure (defined as lack of regular contractions and cervical dilatation of 5 cm within 48 hours or 8 hours of spontaneous or artificial rupture of membranes). Treatment time. Duration of labor. Apgar score < 7. Mode of delivery. Gastrointestinal side‐effects. Uterine hypertonus. | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Low risk | A ‐ Adequate |