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. 2021 Aug 30;9(8):e002551. doi: 10.1136/jitc-2021-002551

Table 2.

Scoring matrix

Condition Assigned point value
Is this mutation not present in the highest frequency cluster as determined by PyClone? 1
Is the AF/MSAF ratio for this mutation <10%? 1
Is this mutation only detected in ctDNA or tissue DNA? 1

AF, allele frequency; ctDNA, circulating tumor DNA; MSAF, maximum somatic allele frequency.