Table 1.

Patients’ and treatments’ characteristics (n = 25)

Patients’ characteristics (n = 25)
Sex ratio (M/F), n			20/5
Age (years), median (min-max)			59 (45-84)
Performance status (OMS)
	0		13
	1		12
BMI, median (min-max)			22.2 (17.9-35.5)
Previous tumor
Previous tumor location
	Oropharynx		8
	Occult primary		8
	Oral cavity		4
	Larynx		3
	Nasopharynx		1
	Hypopharynx		1
Previous treatment
	EBRT alone		21
	EBRT + BT		4
	Chemotherapy		12
	Surgery		18
Previous RT dose delivered (Gy), median (min-max)
	EBRT alone		62 (50-70)
	EBRT + BT		65 (50-72)
Dose at recurrent/second tumor volume (Gy), median (min-max)
	EBRT + BT		50 (50-70)
Second or recurrent tumor
Recurrent/second cancer
	Recurrent		4
	Second cancer		21
Delay (first – salvage RT) (months), median (min-max)			59 (10-214)
Tumor location
	Base of tongue		12
	Mobile tongue		6
	Floor of the mouth		2
	Tonsil		2
	Vallecula		2
	Soft palate		1
T stage
	T1 (< 2 cm)		7
	T2 (2-4 cm)		11
	T3 (> 4 cm)		3
	T4 (adjacent organs)		1
	Tx		3
N stage
	N0		21
	N+		2
	Nx		2
Salvage treatment
Surgery
	Total		22
	R2		1
	R1		20
	Rx		1
Chemotherapy
	Neoadjuvant		3
	Concomitant with EBRT		1
Radiotherapy
	Exclusive BT		15
	EBRT + BT		10
Brachytherapy
	LDR (n)		18
	No. of loops: median (min-max)		3 (2-5)
	PDR (n)		7
	No. of catheters: median (min-max)		6 (4-8)
RT dose (Gy)
	Combined BT: median (min-max)		25 (15-48)
	Exclusive BT: median (min-max)		50 (40-64)
	EBRT: median (min-max)		36 (12-60)
	Total treatment: median (min-max)		57 (40-70)
Cumulative dose (Gy) (previous + salvage RT), median (min-max)			110 (90-140)
Delay EBRT – BT (days), median (min-max)			16 (–36-21)

BT – brachytherapy, EBRT – external beam radiotherapy, RT – radiotherapy, LDR – low-dose-rate, PDR – pulsed-dose-rate, n – number