Comparison 1. Low‐dose colchicine versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1.1 Proportion with 50% or greater decrease in pain score from baseline	1		Risk Ratio (M‐H, Random, 95% CI)	Totals not selected
1.1.1 24 hours	1		Risk Ratio (M‐H, Random, 95% CI)	Totals not selected
1.1.2 32 hours	1		Risk Ratio (M‐H, Random, 95% CI)	Totals not selected
1.2 Total adverse events	1		Risk Ratio (M‐H, Random, 95% CI)	Totals not selected
1.3 Gastrointestinal adverse events (diarrhoea, vomiting or nausea)	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
1.4 Serious adverse events	1		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
1.5 Withdrawals due to adverse events	1		Risk Ratio (M‐H, Random, 95% CI)	Totals not selected