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. 2005 Jul 20;2005(3):CD001439. doi: 10.1002/14651858.CD001439.pub2

Azabache 1987 A.

Methods Randomised controlled trial. Randomisation method stated as simple. Patient and surgeon blinded. Unclear blinding of outcome assesor.
Participants 258 eligible patients. 92 excluded before randomisation. 166, 88 males and 78 females enrolled in the study. 
 Age‐range: 6‐71 
 Mean: 23 
 12 patients excluded after randomisation. 
 The study has 2 subgroups (see Azabache 1987 B). 
 In Azabache 1987 A 110 patients enrolled in study.
Interventions Treatment group: Gentamycin 4 mg/kg and Clindamycin 15 mg/kg one hour inter‐operatively hereafter Gentamycin eighthourly and Clindamycin sixhourly for 24 hours if appendix was suppurativ and 72 hours if appendix was gangrenous/perforated. 
 Placebo group: Not stated. Regime as above.
Outcomes Wound infection (Pus in the cellular space under or above the rectusmuscle 3 weeks postoperatively)
Notes No drain treatment.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear