Azabache 1987 B.

Methods	Randomised controlled trial. Randomisation method stated
Participants	258 eligible patients. 92 excluded before randomisation. 166, 88 males and 78 females enrolled in the study. Age‐range: 6‐71 Mean: 23 12 patients excluded after randomisation. The study has 2 subgroups (see Azabache 1987 A). In Azabache 1987 B 110 patients enrolled in study.
Interventions	Treatment group: Penicilin G 400.000 UI/kg and Chloramphnicol 50 mg/kg one hour intra operatively. Hereafter penicillin G each four hour and chloramphenicol each six hour for 24 hours, if appendix was suppurative and 22 hours if appendix was gangrenous/perforated. Placebo: Not stated. Regimen as above.
Outcomes	Wound infection (Pus in the cellular space under or above the rectusmuscle 3 weeks postoperatively)
Notes	No drain treatment.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear