Eklund 1987.

Methods	Randomised controlled trial. Randomisation by a list of random numbers. Double‐blinded. Unclear blinding of outcome assessor.
Participants	510 eligible patients, 214 males and 296 females enrolled in the study. All patients more than 12 years of age. Patients with perforated appendix, treated with antibiotics for other disease and patients undergoing additional procedure were excluded before randomisation.
Interventions	Treatment group: Tinidazole 2 mg/ ml 200 ml topical peroperatively. Placebo group: Saline 200 ml topical peroperatively.
Outcomes	Woundinfection (Wound discharge visible pus either spontaneously or after debridement).
Notes	No comments on drain treatment. 180 patients had normal appendix.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	A ‐ Adequate