| Methods |
Randomised controlled trial. Randomisation based on a computer list kept by the hospital pharmacist. Triple‐blinded |
| Participants |
165 eligible patients. 26 excluded after randomisation. 139, 74 males and 65 females enrolled in the study. Patients with perforated appendix and different infections such as pelvic inflammatory disease, were excluded after randomisation.
Patients with allergy to penicillin og cephalosporins, antibiotic administration 48 hours before surgery, expectation of need for antibiotic treatment in the immediate postoperative periode and impaired renal or hepatic function were excluded before randomisation. |
| Interventions |
Treatment group: Cephaloridine 50 mg/kg i.m. The first dose given with preanaesthetic medication and postoperatively x4 daily for 2 days.
Placebo group: Not stated: Regime like the treatment group. |
| Outcomes |
Wound infection (Not defined). |
| Notes |
No comments on drain treatment |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Low risk |
A ‐ Adequate |
