Söderquist 1995 A.
Methods | Randomised controlled trial Randomisation method not stated | |
Participants | 857 eligible patients. 313 patients excluded after randomisation. 544 patients enrolled in study. Alle children. Patients with perforated appendicitis were excluded. Patients allergic to antibiotics or recieving antibiotic within 72 hours before surgery were excluded. 193 patients received treatment compared to 176 in the control group | |
Interventions | Treatment group: metronidazole 20 mg/ kg IV 1 hour preoperatively. Placebo group: No treatment | |
Outcomes | Wound infection (subcutaneus abscess with suppuration confirmed by spontaneus wound rupture debriemnt or incision) Intrabadominal absces (absces within the intraabdominal cagvity diagnosed at operation or by rectal examination, x‐ray or ultrasound) | |
Notes | No comment on drain treatment | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |