Söderquist 1995 B.

Methods	Randomised controlled trial Randomisation method not
Participants	857 eligible patients. 313 patients excluded after randomisation. 544 patients enrolled in study. Alle children. Patients with perforated appendicitis were excluded. Patients allergic to antibiotics or recieving antibiotic within 72 hours before surgery were excluded. 175 patients received treatment compared to 176 in the control group.
Interventions	Treatment group: Metronidazole 20 mg/kg + cefuroxime 50 mg/kg iv 1 hour preoperatively. Placebogroup: no treatment
Outcomes	Wound infection (subcutaneus abscess with suppuration confirmed by spontaneus wound rupture debriemnt or incision) Intrabadominal absces (absces within the intraabdominal cagvity diagnosed at operation or by rectal examination, x‐ray or ultrasound)
Notes	No comment on drain treatment
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear