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. 2005 Jul 20;2005(3):CD001439. doi: 10.1002/14651858.CD001439.pub2

Tanner 1980.

Methods Randomised controlled trial. Randomisation method not stated. 
 Patient blinded. Unclear blinding of surgeon and outcome‐assessor.
Participants 111 eligible patients. 7 patients excluded. 104, 51 males and 53 females enrolled in the study. 
 Age‐range 8‐71 
 Mean: Treatment group: 26 +/‐ 14 (s.d.), placebo group: 25 +/‐ 15 (s.d)
Interventions Treatment group: Metronidazole 1 g suppositorium preoperatively. 
 Placebo group: Glycerine supp preoperatively.
Outcomes Wound infection (Presence of pus or a purulent exudate at the wound).
Notes Drain treatment to all patients with perforated appendix.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear