Winslow 1983.
Methods | Randomised controlled trial. Randomisation by the last number in the patients birthday. Triple‐blinded. | |
Participants | 147 eligible patients. 44 excluded after randomisation. 103 enrolled in the study. Age‐range 4‐67. Mean 22. Patients receiving antibiotics 72 hours prior of surgery, had allergy to cephalosporins or penicillin, had impaired renal function and serious underlying disease, were excluded before randomisation | |
Interventions | Treatment group: Cefoxitin 1 g (children 20‐40 mg/kg/dose) IV peroperatively and 6 and 12 hours postoperatively. Placebo group: Saline regime as above. | |
Outcomes | Wound infection (Not defined). Postoperative intra abdominal abscess (Not defined) Length of stay in hospital | |
Notes | No drain treatment. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | High risk | C ‐ Inadequate |