Johnstone 2002.

Methods	Randomised controlled trial (1990 to 1994)
Participants	Individuals with stage IIIA (T1‐T3N2MO) NSCLC. Histologically confirmed N2 disease at mediastinoscopy or anterior mediastinotomy
Interventions	Intervention group: induction chemotherapy followed by surgical resection; Control group: Induction chemotherapy followed by radiotherapy (64Gy). Patients stratified according bulky N2 disease (visible on plain chest radiography) versus other N2 disease
Outcomes	Toxicity, treatment related morbidity and mortality. Overall survival at 4 years.
Notes	C‐factor staging : C3 Staging classification criteria not described Trial terminated early.
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Unclear risk	Information not reported
Allocation concealment?	Unclear risk	Information not reported
Blinding? All outcomes	Unclear risk	Information not reported
Incomplete outcome data addressed? All outcomes	High risk	Description of withdrawals and losses to follow up not complete. 75 patients entered in the study including 12 patients entered but then not randomised after induction. 2 patients ineligible and not included, leaving 29 in surgical group and 32 in the radiotherapy group that were included in the analysis. 2 patients lost to follow up but it was not stated which group or groups they were lost from however all others were followed for at least 48 months.