van Meerbeeck 2007.
Methods | Randomised controlled trial (1994‐2002) | |
Participants | Patients had histologic or cytologic proven stage IIIA N2 disease. | |
Interventions | Intervention:Three cycles of platinum‐based induction chemotherapy followed by surgery Control group: Three cycles of platinum‐based induction chemotherapy followed by definitive radiotherapy |
|
Outcomes | Five‐year overall survival, progression‐free survival, toxicity and mortality | |
Notes | C factor for staging C3 | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Low risk | Computer generated |
Allocation concealment? | Low risk | Central allocation (European Organisation and Treatment of Cancer Data Centre) |
Blinding? All outcomes | Unclear risk | None described |
Incomplete outcome data addressed? All outcomes | Low risk | There were no losses to follow up for the outcome of overall survival in those patients who were randomly assigned. |