Daneman 1961.

Methods	parallel group trial. Variable duration with evaluations done at 1 month and 2 months.
Participants	195 outpatients, age range 17‐75, 69% women
Interventions	imipramine mean dose 133mg and atropine 1.25 mg
Outcomes	4 "response to treatment" categories
Notes	not clear if response to treatment, which was based on ratings of a list of symptoms, was rated blind.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Low risk	A ‐ Adequate