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| Methods | crossover trial of 4 weeks with results of first period of 2 weeks reported as for parallel groups. | |
| Participants | 50 outpatients, mean age 42 (range 22‐71); 76% women | |
| Interventions | imipramine 150mg atropine 0.6mg | |
| Outcomes | Total Distress Score, Morale Loss Scale, doctors and patients overall estimate of condition as better, same, worse. | |
| Notes | ||
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment (selection bias) | Unclear risk | B ‐ Unclear |
