Weintraub 1963.

Methods	parallel group study. Duration 4 weeks.
Participants	89 inpatients, 60% women, mean age 51 (range 19‐73)
Interventions	imipramine 150 mg atropine 0.6mg
Outcomes	improvement rated in three catgeories by ward doctor and hospital director
Notes	discrepant ratings with ward doctor rating drug group as more improved and finding greater drug placebo difference. Blind tested. Neither rater guessed medication group better than chance but both raters rated those they guessed to be on the drug as significantly more improved (p<0.1).
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Unclear risk	B ‐ Unclear