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. 2016 Aug 9;2016(8):CD003380. doi: 10.1002/14651858.CD003380.pub4

Sethi 2010.

Methods Design: RCT
Conducted by the team who developed the intervention: no
Participants Description: targeted
Cut‐point for inclusion for indicated studies: not specified
What risk was basis of inclusion for selected studies: mild to moderate depression according to DASS‐21 scores
Diagnostic interview to exclude those with current and/or past episodes of depression: those with past episodes of depression not excluded, however, those with current depression, as indicated by extremely high scores on the DASS‐21, were excluded
Baseline severity of depression: DASS‐21‐d: 18.20 (moderate)
Mean age: 19.5
Age range: 18 to 23
Percentage male: 21%
Setting: university
State what psychiatric diagnoses were excluded: exclusion criteria not stated
Suicide risk excluded: exclusion criteria not stated
Parents with history of schizophrenia/bipolar disorder excluded: exclusion criteria not stated
Country: Australia
Interventions Broad category: CBT (for further information on intervention components, see Table 3)
Manualised: N/A as MoodGYM freely available to access
Online: yes
Name of programme: MoodGYM
Number of sessions: 3 sessions plus 2 assessment‐only sessions
Length of sessions: between 20 to 40 minutes
Intensity (total number of hours): up to 3.33 hours
Duration of treatment period: 3 weeks
Group size: N/A (individual‐based intervention)
Delivered by: N/A (self‐monitoring)
Fidelity: online, therefore standardised
Type of comparison: NT
Outcomes Diagnosis: N/A
Name of self‐report depression measure: DASS‐21‐d
Name of clinical report depression measure: N/A
Name of anxiety measure: DASS‐21‐a
Name of general functioning measure: N/A
Assessment points: post‐intervention
Notes Author contacted for methodological detail: no
Author contacted for treatment manual: N/A as MoodGYM freely available to access
Author contacted for outcome data: no
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk No information specified
Allocation concealment (selection bias) Unclear risk No information specified
Blinding (performance bias and detection bias) 
 Subjects High risk The nature of the trial suggests it is unlikely participants could have remained blind to the fact they were allocated to a non‐treatment control group. However, without access to the participant information sheets and PLS, level of blinding cannot be ascertained.
Blinding (performance bias and detection bias) 
 Assessors Unclear risk Outcomes self‐reported. Assessor blinding therefore not applicable.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Proportion of participants with incomplete post‐intervention self‐reported depression scores: 0%
Means and SDs used in meta‐analysis based on what data: observed cases
Intention‐to‐treat analyses: N/A as 0% dropouts
Selective reporting (reporting bias) Unclear risk Protocol not available
Other bias Low risk Trial not conducted by those who developed the intervention
Implementation integrity Low risk Implementation integrity assessed: N/A (standardised)
Implementation integrity adequate: N/A
Implementation integrity reported: N/A