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. 2016 Aug 9;2016(8):CD003380. doi: 10.1002/14651858.CD003380.pub4

Stice 2006.

Methods Design: RCT
Conducted by the team who developed the intervention: yes
Participants Description: targeted
Cut‐point for inclusion for indicated studies: CES‐D ≥ 20.0
What risk was basis of inclusion for selected studies: N/A
Diagnostic interview to exclude those with current or previous depression: diagnostic interview undertaken and those with current depression indicated by BDI ≥ 30.0 were excluded. Those with previous episodes of depression not excluded.
Baseline severity of depression: BDI: 19.9 (mild‐moderate)
 
Mean age: 18.4
Age range: 15 to 22
Percentage male: 30.0%
Setting: school
 
State what psychiatric diagnoses were excluded: none
Suicide risk excluded: no
Parents with history of schizophrenia/bipolar disorder excluded: no
 
Country: USA
Interventions Broad category: CBT (for further information on intervention components, see Table 3)
Manualised: yes
Online: no
Name of programme: The Blues Group
Number of sessions: 4 sessions
Length of sessions: 60 minutes
Intensity (total number of hours): 4 hours
Duration of treatment period: 4 weeks
Group size: 6 to 10
Delivered by: students
Fidelity: not assessed
Type of comparison: WL
Outcomes Diagnosis: BDI ≥ 30.0
Name of self‐report depression measure: BDI
Name of clinical report depression measure: N/A
Name of anxiety measure: N/A
Name of general functioning measure: N/A
Assessment points: post‐intervention and 6 months (short‐term)
Notes Author contacted for methodological detail: no
Author contacted for treatment manual: yes (provided)
Author contacted for outcome data: no
Coding for depression severity at baseline: where baseline severity was mild to moderate as in this trial, it was rated as mild.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk No information specified
Allocation concealment (selection bias) Unclear risk No information specified
Blinding (performance bias and detection bias) 
 Subjects High risk The nature of the trial suggests it is unlikely participants could have remained blind to the fact they were allocated to a wait‐list control group. However, without access to the participant information sheets and PLS, level of blinding cannot be ascertained.
Blinding (performance bias and detection bias) 
 Assessors Unclear risk Outcomes self‐reported. Assessor blinding therefore not applicable.
Incomplete outcome data (attrition bias) 
 All outcomes High risk Proportion of participants with incomplete post‐intervention self‐reported depression scores: 18.0% by 6 months
Means and SDs used in meta‐analysis based on what data: observed cases
Intention‐to‐treat analyses: full information maximum likelihood ratio based on expectation‐maximisation algorithm
Selective reporting (reporting bias) Unclear risk Protocol not available
Other bias High risk Trial conducted by those who developed the intervention
Implementation integrity Unclear risk Implementation integrity assessed: unclear if assessed
Implementation integrity adequate: N/A
Implementation integrity reported: N/A