| Methods |
DIAZEPAM
Country: China
Recruitment: no details |
| Participants |
118 smokers, (111 males, 7 females) >20cigs/day |
| Interventions |
1. Diazepam ('Valium') recommended dosage 7.5mg/day for 4 wks
2. Clonidine, recommended dosage 0.225 mg/day for 4 wks
3. Matched placebo
All participants had 3 individual sessions with a psychiatrist |
| Outcomes |
Continuous abstinence at follow up on average 4.5ms from end of treatment. No biochemical validation, but confirmation sought from family and co‐workers. |
| Notes |
Efficacy of clonidine has been assessed in a separate Cochrane review (Gourlay 2004) |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Randomized, method not described |
| Allocation concealment (selection bias) |
Unclear risk |
No details given |
