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. 2020 Jul 1;2020(7):CD013663. doi: 10.1002/14651858.CD013663

Comparison 3. Intrauterine balloon tamponade plus normal care (misoprostol) versus normal care (misoprostol).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
3.1 Mortality due to bleeding 1 116 Risk Ratio (M‐H, Fixed, 95% CI) 6.21 [0.77, 49.98]
3.2 Hysterectomy to control bleeding 1 116 Risk Ratio (M‐H, Fixed, 95% CI) 4.14 [0.48, 35.93]
3.3 All cause mortality 1 116 Risk Ratio (M‐H, Fixed, 95% CI) 6.21 [0.77, 49.98]
3.4 Mortality from causes other than bleeding 1 116 Risk Ratio (M‐H, Fixed, 95% CI) Not estimable
3.5 Number of women with total blood loss 1000 mL or more after randomisation 1 113 Risk Ratio (M‐H, Fixed, 95% CI) 1.52 [1.15, 2.00]
3.6 Blood transfusion (red cell or whole blood) 1 116 Risk Ratio (M‐H, Fixed, 95% CI) 1.49 [0.88, 2.51]
3.7 Post‐randomisation additional surgical interventions used to control bleeding (arterial ligation, compressive, uterine sutures, arterial embolisation, laparotomy) 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
3.7.1 Uterine compression sutures 1 116 Risk Ratio (M‐H, Fixed, 95% CI) 5.17 [0.25, 105.44]
3.7.2 Artery ligation 1 116 Risk Ratio (M‐H, Fixed, 95% CI) 1.38 [0.32, 5.90]
3.8 Admission to higher level of care 1 116 Risk Ratio (M‐H, Fixed, 95% CI) 1.29 [0.55, 3.04]
3.9 Side effects of the intervention (e.g. trauma, necrosis) 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
3.9.1 Severe shivering, diarrhoea, vomiting or high temperature 1 116 Risk Ratio (M‐H, Fixed, 95% CI) Not estimable