Comparison 1. Pramipexole versus bromocriptine.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 UPDRS ADL scores (part II)			Other data	No numeric data
2 UPDRS motor scores (part III)			Other data	No numeric data
3 UPDRS complications scores (part IV)			Other data	No numeric data
4 Hoehn and Yahr stage			Other data	No numeric data
5 Schwab and England scale			Other data	No numeric data
6 Levodopa dose reduction (mg)	1	163	Mean Difference (IV, Fixed, 95% CI)	29.40 [‐21.91, 80.71]
7 Off time reduction (hours)	1	152	Mean Difference (IV, Fixed, 95% CI)	1.40 [0.03, 2.77]
8 Dyskinesia rating scale			Other data	No numeric data
9 Adverse events ‐ Nausea	1	163	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.99 [0.53, 1.87]
10 Adverse events ‐ Postural hypotension	1	163	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.87 [0.47, 1.61]
11 Adverse events ‐ Hallucinations	1	163	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.20 [0.48, 2.98]
12 Adverse events ‐ Confusion	1	163	Peto Odds Ratio (Peto, Fixed, 95% CI)	2.06 [0.76, 5.60]
13 Adverse events ‐ Dyskinesia	1	163	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.83 [0.44, 1.53]
14 All cause withdrawal rate	1	163	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.00 [0.47, 2.14]