Comparison 1. Supervised maintenance programme vs usual care.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1.1 QoL SGRQ total at time point six to 12 months following completion of pulmonary rehabilitation	5	276	Mean Difference (IV, Random, 95% CI)	‐1.57 [‐4.93, 1.78]
1.2 QoL SGRQ Symptoms at time point six to 12 months following completion of pulmonary rehabilitation	4	234	Mean Difference (IV, Random, 95% CI)	‐0.29 [‐6.32, 5.73]
1.3 QoL SGRQ Activity at time point six to 12 months following completion of pulmonary rehabilitation	4	234	Mean Difference (IV, Random, 95% CI)	‐2.57 [‐8.05, 2.90]
1.4 QoL SGRQ Impact at time point six to 12 months following completion of pulmonary rehabilitation	4	234	Mean Difference (IV, Random, 95% CI)	‐2.08 [‐7.39, 3.23]
1.5 QoL CRQ total score at time point six to 12 months following completion of pulmonary rehabilitation	4	258	Mean Difference (IV, Random, 95% CI)	0.54 [0.04, 1.03]
1.6 QoL CRQ Dyspnea time point six to 12 months following completion of pulmonary rehabilitation	4	210	Mean Difference (IV, Random, 95% CI)	0.28 [‐0.51, 1.06]
1.7 QoL CRQ Fatigue at time point six to 12 months following completion of pulmonary rehabilitation	4	210	Mean Difference (IV, Random, 95% CI)	0.38 [0.04, 0.73]
1.8 QoL CRQ Emotion at time point six to 12 months following completion of pulmonary rehabilitation	4	210	Mean Difference (IV, Random, 95% CI)	0.57 [0.18, 0.96]
1.9 QoL CRQ Mastery at time point six to 12 months following completion of pulmonary rehabilitation	4	210	Mean Difference (IV, Random, 95% CI)	0.54 [0.05, 1.04]
1.10 QoL SF36 Physical at time point six to 12 months following completion of pulmonary rehabilitation	2	219	Mean Difference (IV, Random, 95% CI)	‐0.72 [‐3.86, 2.43]
1.11 QoL SF36 Mental at time point six to 12 months following completion of pulmonary rehabilitation	2	219	Mean Difference (IV, Random, 95% CI)	‐0.42 [‐3.56, 2.72]
1.12 QoL EuroQoL‐5D at time point six to 12 months following completion of pulmonary rehabilitation	2	150	Mean Difference (IV, Random, 95% CI)	0.00 [‐0.08, 0.08]
1.13 QoL CAT at time point six to 12 months following completion of pulmonary rehabilitation	2	147	Mean Difference (IV, Random, 95% CI)	‐5.88 [‐8.39, ‐3.37]
1.14 6MWD at time point six to 12 months following completion of pulmonary rehabilitation	10	639	Mean Difference (IV, Random, 95% CI)	25.90 [‐1.04, 52.84]
1.15 ISWT at time point six to 12 months following completion of pulmonary rehabilitation	2	111	Mean Difference (IV, Random, 95% CI)	4.15 [‐44.93, 53.23]
1.16 ESWT at time point six to 12 months following completion of pulmonary rehabilitation	5	369	Mean Difference (IV, Random, 95% CI)	26.87 [‐60.58, 114.33]
1.17 Hospital admission (all‐causes) odds time point at six to 12 months following completion of pulmonary rehabilitation	2	142	Odds Ratio (M‐H, Random, 95% CI)	0.71 [0.14, 3.69]
1.18 Hospital admission (all‐causes) rate at time point six to 12 months following completion of pulmonary rehabilitation	3		Mean Difference (IV, Random, 95% CI)	Subtotals only
1.19 Exacerbation odds at time point six to 12 months following completion of pulmonary rehabilitation	3	280	Odds Ratio (M‐H, Random, 95% CI)	0.73 [0.26, 2.02]
1.20 Exacerbation rate at time point six to 12 months following completion of pulmonary rehabilitation	3		Mean Difference (IV, Random, 95% CI)	Subtotals only
1.21 Mortality time point six to 12 months following completion of pulmonary rehabilitation	6	755	Odds Ratio (M‐H, Random, 95% CI)	0.73 [0.36, 1.51]