| Methods |
'Randomly allocated', no further information. |
| Participants |
10 women with severe pre‐eclampsia; BP > 160/110 mmHg and at least 1g/litre proteinuria. No pre‐existing hypertension, renal disease, heart disease or antihypertensives. Not in labour. All women had a Swan Ganz catheter inserted. |
| Interventions |
Expansion: 200 ml 3.5% haemaccel, then successive 200 ml over 30 minutes until pulmonary capillary wedge pressure increased by at least 16 mmHg. Then hydralazine 25 mg/200 ml infused to keep DBP 90‐110 mmHg.
Control: hydralazine as above, but without prior infusion. |
| Outcomes |
Women: caesarean section, mean gestation, change in pulmonary wedge pressure, cardiac index and systemic vascular resistance.
Baby: birthweight, Apgar at 1 and 5 minutes. |
| Notes |
Four women had magnesium sulphate before entry, the others started it after hydralazine. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Unclear risk |
B ‐ Unclear |
