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The illustration of tumor location of (a) no extensive disease and (b) extensive disease. No extensive disease was defined as no Gleason pattern 4/5 in bilateral lobes, no extraprostatic extension, no seminal vesicle involvement, and no lymph node invasion. Extensive disease was defined as (i) Gleason pattern 4/5 in bilateral lobes, or (ii) extraprostatic extension, or (iii) seminal vesicle involvement, or (iv) lymph node invasion.
