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. 2021 Aug 27;14:331–347. doi: 10.2147/IJNRD.S326399

Table 4.

Multivariate Linear Regression Analysis for Predictors of Increased CC-IMT and S. iFGF23 in SLE Patients with and without Lupus Nephritis (LN)

A: Outcome: Increased CC-IMT
G2: SLE Patients (N = 20) G3: LN Patients (N = 28)
Model R2 0.614 Model R2 0.339
Model Significance 0.029* Model Significance 0.042*
Predictors β Coefficient Adjusted P Predictors β Coefficient Adjusted P
Cum_S 0.833 0.05* S. iFGF23 0.442 0.09
S. iFGF23 0.195 0.475 Cum_S − 0.053 0.792
S. Phosphorus 0.043 0.86 Dyslipidaemia 0.163 0.43
Haemoglobin − 0.420 0.089 Proteinuria 0.099 0.64
Dyslipidaemia − 0.364 0.214
Age − 0.308 0.292
*Significant (P < 0.05).
B: Outcome: Increased S. iFGF23
G2: SLE Patients (N = 20) G3: LN Patients (N = 28)
Model R2 0.611 Model R2 0.463
Model Significance 0.005** Model Significance 0.028*
Predictors β Coefficient Adjusted P Predictors β Coefficient Adjusted P
S. LDL 0.072 0.73 SMART Score 0.233 0.277
S. Phosphorus 0.397 0.049* Dyslipidaemia 0.231 0.209
S. Creatinine 0.276 0.197 Proteinuria 0.466 0.026*
Cum_S 0.314 0.121 S. Creatinine − 0.046 0.828
Av_S 0.059 0.762
S. Phosphorus 0.011 0.954
*Significant (P < 0.05), **Highly significant (P < 0.01).

Abbreviations: CC-IMT, common carotid intima-media thickness; Cum_S, cumulative steroid dose; S, serum; iFGF23, intact fibroblast growth factor 23; LDL, low-density lipoproteins; Av_S, average steroid dose.