Table 1.
Clinical Characteristics of the Patients with CHD After Admission
| Variables | NGAL <102.5 ng/mL (n=316) | NGAL ≥102.5 ng/mL (n=317) | P Value |
|---|---|---|---|
| Age (years) | 71.6 (67.4–77.8) | 72.1 (68.2–79.2) | 0.098 |
| Gender (male) | 174 (55.1) | 161 (50.8) | 0.215 |
| BMI (kg/m2) | 25.4 (24.3–28.7) | 26.2 (23.1–29.4) | 0.018 |
| Smoker | 63 (19.9) | 84 (26.5) | 0.007 |
| Drinker | 49 (15.5) | 79 (24.9) | <0.001 |
| CVD history on admission | 52 (15.5) | 101 (31.9) | <0.001 |
| Exercise regularly | 124 (39.2) | 101 (31.8) | 0.064 |
| Diabetes mellitus | 12 (3.8) | 34 (10.7) | <0.001 |
| Heart rate (beats/min) | 83±7 | 85±6 | 0.389 |
| CV mortality during follow-up | 11 (3.5) | 32 (10.1) | <0.001 |
| Systolic BP (mmHg) | 129 (120–142) | 133 (124–146) | 0.011 |
| Diastolic BP (mmHg) | 78 (72–85) | 80 (73–89) | 0.012 |
| Preserved LVEF | 201 (63.6) | 164 (51.7) | 0.011 |
| Hospital stay (days) | 10 (5–11) | 12 (7–14) | 0.112 |
| Medications | |||
| Diuretics | 286 (90.5) | 310 (97.8) | 0.071 |
| ACE inhibitors | 218 (69.0) | 253 (79.8) | 0.058 |
| Beta-blockers | 132 (41.8) | 89 (28.1) | 0.52 |
| Laboratory measurements | |||
| NGAL (ng/mL) | 73.4±6.51 | 146.5±13.5 | <0.001 |
| SCr (µmol/L) | 85.6±7.3 | 99.6±9.5 | 0.009 |
| BUN (mmol/L) | 5.6±3.4 | 7.1±3.9 | 0.014 |
| FBG (mmol/L) | 5.97 (4.53–7.69) | 6.34 (5.12–8.83) | 0.038 |
| ALB (g/L) | 41.5 (38.9–44.2) | 37.6 (35.2–40.4) | <0.001 |
| Hb (g/L) | 122 (113–127) | 116 (108–133) | 0.019 |
| hs-CRP (mg/L) | 6.17 (1.89–21.75) | 10.91 (3.24–28.55) | <0.001 |
| BNP (pg/mL) | 1432±245 | 1395±239 | 0.43 |
| TG (mmol/L) | 1.39±0.41 | 2.14±0.54 | <0.001 |
| LDL (mmol/L) | 2.16 (1.49–2.54) | 2.59 (1.53–2.81) | 0.001 |
| HDL (mmol/L) | 0.79 (0.60–1.01) | 0.71 (0.54–0.95) | 0.104 |
| TC (mmol/L) | 3.67±0.92 | 4.31±1.23 | 0.007 |
Note: Data are shown as median (range), n (%) or mean ± SD.