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. 2021 Sep 1;12(6):1389–1408. doi: 10.14336/AD.2021.0406

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Copyright: © 2021 Sil et al.

this is an open access article distributed under the terms of the creative commons attribution license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 2. — Expression of astrocytic Aβ mOC64 in the FC and BG of morphine-dependent macaques. Representative immuno-histochemistry photomicrographs showing differential expression of Aβ mOC64 protein in GFAP-positive astrocytes in the FC (A) and BG (B) of morphine-dependent macaques. Scale bar, 20 μm. Quantitative analysis of percent of GFAP positive (C) and negative astrocytes (D) colocalized with Aβ mOC64 protein in saline and morphine-dependent macaque. Ten fields from FC and BG/macaque were analyzed from n= 4 macaques per group. Data are presented as mean±SEM. Student t test was used to determine the statistical significance: $P< 0.001 versus saline. Abbreviations: Aβ, amyloid beta, GFAP, glial fibrillary acidic protein.