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. 2021 Aug 23;2021:9920962. doi: 10.1155/2021/9920962

Figure 1.

Figure 1

Effects of CIG on locomotor activity of SAMP8 mice at young and aged SAMP8 mice. (a) Quantitative analysis of total times in locomotor activity of 6-month-old SAMP8 mice; (b) quantitative analysis of total times in locomotor activity of 14-month-old SAMP8 mice. Data are expressed as the mean ± S.E.M., n = 10∼15 each group. #P < 0.05, ##P < 0.01, SAMP8 model group vs SAMR1 control group; ∗P < 0.05 and ∗∗P < 0.01, drug-treated SAMP8 groups vs. SAMP8 model group. SAMR1, senescence accelerated mouse/resistant 1; R1 + CIG (M), SAMR1 mice treated with CIG at 100 mg/kg; SAMP8, senescence accelerated mouse/prone 8; P8 + CIG (L), SAMP8 mice treated with CIG at 50 mg/kg; P8 + CIG (M), SAMP8 mice treated with CIG at 100 mg/kg; P8 + CIG (L), SAMP8 mice treated with CIG at 200 mg/kg; P8 + oxi, and SAMP8 mice treated with oxiracetam at 360 mg/kg.