Table 3.
Cox regression results of lung cancer patients.
| Factors | Univariate analysis | Multivariate analysis | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| B | Wald | p | HR | 95%CI | B | Wald | p | HR | 95%CI | |
| CHM | −0.327 | 15.965 | <0.001 | 0.721 | 0.614–0.846 | −0.774 | 53.138 | <0.001 | 0.461 | 0.375–0.568 |
| Gender | 0.852 | 98.220 | <0.001 | 2.343 | 1.980–2.773 | 0.347 | 11.359 | 0.001 | 1.414 | 1.156–1.730 |
| Age | 0.032 | 49.518 | <0.001 | 1.032 | 1.023–1.042 | 0.023 | 25.092 | <0.001 | 1.024 | 1.014–1.033 |
| Pathology | ||||||||||
| Adenocarcinoma | 0.036 | 0.043 | 0.836 | 1.036 | 0.739–1.453 | |||||
| Squamous cell cancer | −0.529 | 11.382 | 0.001 | 0.589 | 0.433–0.801 | |||||
| Small cell lung cancer | 0.185 | 0.675 | 0.411 | 1.204 | 0.774–1.872 | |||||
| Others as control | NA | 78.871 | <0.001 | NA | NA | |||||
| Stage | ||||||||||
| I as control | NA | 269.917 | <0.001 | NA | NA | NA | 115.146 | <0.001 | NA | NA |
| II | 0.663 | 12.482 | <0.001 | 1.940 | 1.343–2.802 | 0.460 | 5.868 | 0.015 | 1.584 | 1.092–2.299 |
| IIIA | 1.295 | 80.139 | <0.001 | 3.650 | 2.749–4.846 | 0.882 | 32.380 | <0.001 | 2.417 | 1.783–3.275 |
| IIIB | 1.626 | 130.662 | <0.001 | 5.084 | 3.847–6.718 | 1.072 | 42.996 | <0.001 | 2.922 | 2.121–4.026 |
| IV | 1.620 | 242.732 | <0.001 | 5.054 | 4.122–6.197 | 1.437 | 112.673 | <0.001 | 4.208 | 3.227–5.486 |
| Surgery | −0.997 | 148.926 | <0.001 | 0.369 | 0.314–0.433 | −0.448 | 21.853 | <0.001 | 0.639 | 0.530–0.771 |
| Chemotherapy | −0.343 | 61.861 | <0.001 | 0.710 | 0.651–0.773 | −0.157 | 2.437 | 0.119 | 0.855 | 0.702–1.041 |
| Radiotherapy | −0.365 | 61.164 | <0.001 | 0.694 | 0.634–0.761 | 0.059 | 0.332 | 0.564 | 1.061 | 0.867–1.298 |
| Interventional therapy | 0.458 | 2.062 | 0.151 | 1.581 | 0.846–2.955 | |||||
| Targeted therapy | −0.339 | 47.864 | <0.001 | 0.712 | 0.647–0.784 | −0.140 | 1.734 | 0.188 | 0.870 | 0.707–1.071 |
| Family history | −0.339 | 9.413 | 0.002 | 0.712 | 0.574–0.885 | 0.028 | 0.059 | 0.807 | 1.029 | 0.820–1.291 |
| Smoking | 0.693 | 70.852 | <0.001 | 1.999 | 1.701–2.349 | 0.192 | 3.291 | 0.070 | 1.212 | 0.985–1.491 |
| Drinking | 0.600 | 23.410 | <0.001 | 1.822 | 1.429–2.323 | 0.191 | 1.879 | 0.170 | 1.210 | 0.921–1.589 |