Table 1.
Baseline characteristics before and after matching for the rVIII-SingleChain (phase I/III IPD) and rAHF-PFM-2004 prophylactic treatment populations [16, 28]
| Before matching | After matching | |||
|---|---|---|---|---|
| rVIII-SingleChain | rAHF-PFM-2004 | rVIII-SingleChain‡ | rAHF-PFM-2004 | |
| Number of subjects | 146† | 111 | 146† | 111 |
| Age > 18 years, % | 84.2 | 44.1 | 44.1 | 44.1 |
| Race, % white | 69.9 | 92.8 | 92.8 | 92.8 |
| Weight (kg), mean | 74.0 | 65.8 | 65.8 | 65.8 |
| Height (cm), mean | 174.4 | 169.3 | 169.3 | 169.3 |
IPD individual patient data, rFVIII recombinant factor VIII
†One patient was excluded in the comparison of the annualized rFVIII consumption because of missing data on this outcome. Baseline characteristics for these 145 patients can be found in Supplementary Material Table S2
‡The effective sample size of rVIII-SingleChain after balancing with the rAHF-PFM-2004 population was 25.1