Table 1.
Correlation between CMTM3 and clinicopathological features in pancreatic cancer
| Characteristics | CMTM3 expression | |||||
|---|---|---|---|---|---|---|
| TCGA cohort | GPPH cohort | |||||
| High (n=83) | Low (n=83) | P value | High (n=46) | Low (n=46) | P value | |
| Age | 0.6324 | 0.8169 | ||||
| <60 | 34 | 30 | 12 | 14 | ||
| ≥60 | 49 | 53 | 34 | 32 | ||
| Gender | 0.7556 | 0.5312 | ||||
| Male | 43 | 46 | 22 | 26 | ||
| Female | 40 | 37 | 24 | 20 | ||
| AJCC stage | 0.4717 | 0.2023 | ||||
| I | 7 | 12 | 12 | 6 | ||
| II | 71 | 66 | 31 | 34 | ||
| III | 1 | 2 | 2 | 4 | ||
| IV | 3 | 1 | 0 | 2 | ||
| Unkonwn | 1 | 2 | 1 | 0 | ||
| Histologic grade | 0.01866 | 0.008396 | ||||
| G1 | 8 | 21 | 3 | 5 | ||
| G2 | 50 | 45 | 28 | 39 | ||
| G3 | 24 | 14 | 12 | 2 | ||
| G4 | 1 | 1 | 0 | 0 | ||
| Unkonwn | 0 | 2 | 3 | 0 | ||
| Tumor size | 0.4611 | 0.09651 | ||||
| <4 | 49 | 53 | 8 | 16 | ||
| ≥4 | 29 | 23 | 38 | 30 | ||
| Unkonwn | 5 | 7 | 0 | 0 | ||
| Lymph nodes positive | 0.1605 | 0.7093 | ||||
| Yes | 63 | 54 | 16 | 14 | ||
| No | 18 | 27 | 28 | 32 | ||
| Unkonwn | 2 | 2 | 2 | 0 | ||
| Tumor site | 0.07104 | 0.04429 | ||||
| Head of Pancreas | 70 | 58 | 26 | 16 | ||
| Body/Tail of Pancreas | 9 | 18 | 18 | 29 | ||
| Unkonwn | 4 | 7 | 2 | 1 | ||
| Recurrence/Metastasis | 0.02629 | 0.009009 | ||||
| Yes | 28 | 15 | 18 | 6 | ||
| No | 46 | 60 | 28 | 40 | ||
| Unkonwn | 9 | 8 | 0 | 0 | ||
| Diabete mellitus | 0.1551 | 0.7664 | ||||
| Yes | 21 | 13 | 15 | 13 | ||
| No | 50 | 59 | 30 | 33 | ||
| Unkonwn | 12 | 11 | 1 | 0 | ||
| Alcohol history | 0.6226 | 0.169 | ||||
| Yes | 47 | 46 | 25 | 18 | ||
| No | 28 | 34 | 19 | 27 | ||
| Unkonwn | 8 | 3 | 2 | 1 | ||