Table 3.
Univariate and multivariate Cox regression analysis of risk factors associated with disease-free survival
| Clinicopathological variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P Value | HR | 95% CI | P Value | |
| CMTM3 expression (High vs. Low) | 5.61 | 3.91-7.01 | <0.01 | 3.24 | 1.92-4.56 | <0.01 |
| Gender (Male vs. Female) | 1.31 | 0.43-2.19 | 0.72 | |||
| Age (≥50 vs. <50) | 1.42 | 0.78-2.06 | 0.31 | |||
| Tumor site (Head vs. Body/Tail) | 1.56 | 0.89-2.23 | 0.13 | |||
| Tumor size (≥4 cm vs. <4 cm) | 1.89 | 1.21-2.57 | <0.05 | 2.00 | 0.68-3.32 | 0.68 |
| Lymphnodes positive (Yes vs. No) | 2.96 | 1.86-4.06 | <0.01 | 2.47 | 1.26-3.68 | <0.05 |
| AJCC stage (Advanced vs. Early) | 3.21 | 2.09-4.33 | <0.01 | 2.72 | 2.09-3.35 | <0.01 |
| Histologic grade (High vs. Low) | 2.03 | 1.17-2.89 | <0.05 | 1.47 | 0.47-2.47 | 0.35 |