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. 2021 Jul 25;12(19):5712–5722. doi: 10.7150/jca.58979

Figure 5.

Figure 5

lncRNA-H19 attenuated miR-29b-3p-mediated carboplatin sensitivity in EOC cells. SKOV3 and SKOV3-CB cells were transfected with miR-NC, miR-29b-3p, miR-29b-3p+pcDNA3.1, or miR-29b-3p+pcDNA3.1-H19, followed by detection of colony number (A, 200×), cell proliferation (B and C), migration (D, 200×), invasion (E, 200×), and the drug-resistance-related proteins P-gp, MRP1, and LRP (F and G). *P<0.05. IC50, 50% inhibitory concentration. For Figure 5F, lane 1-4 stands for miR-NC, miR-29b-3p, miR-29b-3p + pcDNA3.1, and miR-29b-3p + pcDNA3.1-H19, respectively.