Table 4.

Univariate and multivariate analysis using Cox's proportional hazard model

Variable	n	Univariate a	Multivariate b
		p value	HR c	95% CI d	p-value
Total	81
Sex
Male vs. Female	51 vs. 30	0.357
Age (years)
≥ 65 vs. < 65	43 vs. 38	0.776
BMI (kg/m2)
< 18.5 vs. ≥ 18.5	8 vs. 73	0.080
pStagee
pStage III vs. pStage II	34 vs. 47	< 0.001	3.08	1.41-7.22	0.005
Histological type
Undifferentiated vs. Differentiated	49 vs. 32	0.856
Postoperative peak-CRP (mg/dl)
≥ 8.1 vs. < 8.1	45 vs. 36	0.658
Complication (C-Df ≥ II)
Positive vs. Negative	12 vs. 69	0.480
PIAC (weeks)
≥ 7 vs. < 7	23 vs. 58	0.004	2.45	1.13-5.29	0.024
Cumulative S-1 dose/BSAg (mg/m2)
< 12,000 vs. ≥12,000	40 vs. 41	0.002	3.27	1.43-8.37	0.004

^a Analyzed by Log Rank (Mantel-Cox) test;

^b Analyzed by Cox's proportional hazard model;

^c HR: hazard ratio, ^d CI: confidence interval;

^e Japanese Classification of Gastric Carcinoma;

^f C-D: Clavien-Dindo classification, ^g BSA: body surface area.